Xu Yuan, He Bin
Department of Biomedical Engineering, University of Minnesota, 7-105 BSBE, 312 Church Street, Minneapolis, MN 55455, USA.
Phys Med Biol. 2005 Nov 7;50(21):5175-87. doi: 10.1088/0031-9155/50/21/015. Epub 2005 Oct 19.
We report our theoretical and experimental investigations on a new imaging modality, magnetoacoustic tomography with magnetic induction (MAT-MI). In MAT-MI, the sample is located in a static magnetic field and a time-varying (micros) magnetic field. The time-varying magnetic field induces an eddy current in the sample. Consequently, the sample will emit ultrasonic waves by the Lorentz force. The ultrasonic signals are collected around the object to reconstruct images related to the electrical impedance distribution in the sample. MAT-MI combines the good contrast of electrical impedance tomography with the good spatial resolution of sonography. MAT-MI has two unique features due to the solenoid nature of the induced electrical field. Firstly, MAT-MI could provide an explicit or simple quantitative reconstruction algorithm for the electrical impedance distribution. Secondly, it promises to eliminate the shielding effects of other imaging modalities in which the current is applied directly with electrodes. In the theoretical part, we provide formulae for both the forward and inverse problems of MAT-MI and estimate the signal amplitude in biological tissues. In the experimental part, the experimental setup and methods are introduced and the signals and the image of a metal object by means of MAT-MI are presented. The promising pilot experimental results suggest the feasibility of the proposed MAT-MI approach.
我们报告了对一种新的成像模态——磁感应磁声断层成像(MAT-MI)的理论和实验研究。在MAT-MI中,样本置于静磁场和时变(微)磁场中。时变磁场在样本中感应出涡电流。因此,样本会通过洛伦兹力发射超声波。超声波信号在物体周围收集,以重建与样本中电阻抗分布相关的图像。MAT-MI将电阻抗断层成像的良好对比度与超声成像的良好空间分辨率结合起来。由于感应电场的螺线管性质,MAT-MI具有两个独特特征。首先,MAT-MI可为电阻抗分布提供明确或简单的定量重建算法。其次,它有望消除其他成像模态中因直接用电极施加电流而产生的屏蔽效应。在理论部分,我们给出了MAT-MI正问题和逆问题的公式,并估计了生物组织中的信号幅度。在实验部分,介绍了实验装置和方法,并展示了通过MAT-MI获得的金属物体的信号和图像。有前景的初步实验结果表明了所提出的MAT-MI方法的可行性。