Bernard Y
Service de Cardiologie, Pôle Coeur-Poumons, Hôpital Jean Minjoz, Boulevard Fleming, 25030 Besançon Cedex, France.
J Neuroradiol. 2005 Sep;32(4):266-72. doi: 10.1016/s0150-9861(05)83149-9.
Atherosclerotic plaques of the thoracic aorta are a well-recognized source of systemic embolism, especially cerebral embolism, in patients 60 years of age or older. The most helpful and readily available imaging technique to detect aortic plaques is transesophageal echocardiogram. Aortic plaques>4mm in thickness are the more likely to cause peripheral embolism. Moreover, plaque morphology is important to consider, since ulcerated plaques and plaques with mobile intra-aortic components ("debris") as well as hypoechoic and noncalcified plaques are at the higher risk of embolism. In addition to these common atherosclerotic lesions, rare cases of mobile thromboses of the aortic arch without aortic debris have been described in younger patients. Finally, a particular situation is that of cholesterol embolism following invasive intra-aortic maneuvers on atherosclerotic aortas. While the diagnosis of these lesions is well established, their management and treatment remain controversial.
在60岁及以上的患者中,胸主动脉粥样硬化斑块是公认的系统性栓塞来源,尤其是脑栓塞。检测主动脉斑块最有用且最容易获得的成像技术是经食管超声心动图。厚度大于4毫米的主动脉斑块更有可能导致外周栓塞。此外,斑块形态也很重要,因为溃疡斑块、具有主动脉内活动成分(“碎片”)的斑块以及低回声和非钙化斑块发生栓塞的风险更高。除了这些常见的动脉粥样硬化病变外,年轻患者中也有罕见的无主动脉碎片的主动脉弓活动血栓形成病例。最后,一种特殊情况是在动脉粥样硬化主动脉上进行有创主动脉操作后发生胆固醇栓塞。虽然这些病变的诊断已明确,但它们的管理和治疗仍存在争议。