Forrester S D, Rogers K S, Relford R L
Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg 24061-0442.
J Am Vet Med Assoc. 1992 Jun 1;200(11):1704-6.
Cholangiohepatitis was diagnosed in a dog with a 4-day history of anorexia, vomiting, fever, and icterus. Additional findings included signs of depression, dehydration, hepatosplenomegaly, and abdominal discomfort. Exploratory laparotomy was performed, and specimens of liver, spleen, and bile were obtained. Histologic evaluation of liver and spleen revealed acute, suppurative cholangio-hepatitis and splenitis, respectively. Cultures of liver and bile yielded Klebsiella sp. The dog responded to rehydration and intravenous administration of chloramphenicol. Although uncommon, cholangiohepatitis should be suspected in dogs with anorexia, fever, vomiting, icterus, and signs of abdominal discomfort. Definitive diagnosis requires bacterial cultures of liver and bile. Administration of an appropriate antibiotic should resolve clinical signs.
一只出现厌食、呕吐、发热和黄疸症状4天的犬被诊断为胆管肝炎。其他检查结果包括精神沉郁、脱水、肝脾肿大和腹部不适。进行了剖腹探查术，获取了肝脏、脾脏和胆汁的样本。肝脏和脾脏的组织学评估分别显示为急性化脓性胆管肝炎和脾炎。肝脏和胆汁培养分离出克雷伯菌属。该犬经补液和静脉注射氯霉素后病情好转。胆管肝炎虽然不常见，但对于出现厌食、发热、呕吐、黄疸和腹部不适症状的犬应怀疑此病。确诊需要进行肝脏和胆汁的细菌培养。使用合适的抗生素治疗应能缓解临床症状。
