Gerber G B, Wick R R, Kellerer A M, Hopewell J W, Di Majo V, Dudoignon N, Gössner W, Stather J
B-2400 Mol, De Heylanden 7, European Late Effects Project Group EULEP, Belgium.
Radiat Prot Dosimetry. 2006;118(1):70-7. doi: 10.1093/rpd/nci342. Epub 2005 Oct 21.
The European Radiobiology Archives (ERA), supported by the European Commission and the European Late Effect Project Group (EULEP), together with the US National Radiobiology Archives (NRA) and the Japanese Radiobiology Archives (JRA) have collected all information still available on long-term animal experiments, including some selected human studies. The archives consist of a database in Microsoft Access, a website, databases of references and information on the use of the database. At present, the archives contain a description of the exposure conditions, animal strains, etc. from approximately 350,000 individuals; data on survival and pathology are available from approximately 200,000 individuals. Care has been taken to render pathological diagnoses compatible among different studies and to allow the lumping of pathological diagnoses into more general classes. 'Forms' in Access with an underlying computer code facilitate the use of the database. This paper describes the structure and content of the archives and illustrates an example for a possible analysis of such data.
欧洲放射生物学档案库(ERA)由欧盟委员会和欧洲晚期效应项目组(EULEP)提供支持,与美国国家放射生物学档案库(NRA)以及日本放射生物学档案库(JRA)共同收集了所有仍可获取的关于长期动物实验的信息,包括一些精选的人体研究。这些档案库由一个微软Access数据库、一个网站、参考文献数据库以及关于该数据库使用的信息组成。目前,这些档案库包含了约350,000个个体的暴露条件、动物品系等描述;约200,000个个体的生存和病理学数据可供使用。已注意使不同研究之间的病理诊断具有兼容性,并允许将病理诊断归为更一般的类别。Access中带有底层计算机代码的“表单”便于数据库的使用。本文描述了档案库的结构和内容,并举例说明了对此类数据进行可能分析的一个示例。