Zabel S, Mueller R S, Fieseler K V, Bettenay S V, Littlewood J D, Wagner R
Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Vet Rec. 2005 Oct 22;157(17):505-9. doi: 10.1136/vr.157.17.505.
The records of 15 horses with pemphigus foliaceus diagnosed on the basis of their history, clinical signs, histopathology and the exclusion of differential diagnoses were evaluated with respect to the age of onset, the clinical signs and the diagnostic tests used. There was no apparent breed predisposition. The horses' mean age was nine years, with a range from three months to 25.5 years, three were foals up to six months old and eight were nine years old or older. The most frequent lesions were scaling in 11, crusting in 10 and alopecia in 10, and they appeared most commonly on the face, neck and trunk, in 10 horses for each of these sites. The extremities were involved in nine of the horses, pruritus occurred in seven, and four of the horses had pustules. The clinical signs mostly corresponded with those described in previous reports, but signs of pain were not a prominent feature. Acantholytic cells were identified cytologically in four of six of the horses.
对15匹根据病史、临床症状、组织病理学及排除鉴别诊断而诊断为落叶型天疱疮的马匹记录，就发病年龄、临床症状及所采用的诊断检测进行了评估。没有明显的品种易感性。马匹的平均年龄为9岁，范围从3个月至25.5岁，3匹是6个月龄以下的幼驹，8匹为9岁及以上。最常见的病变为11匹马出现脱屑，10匹马出现结痂，10匹马出现脱毛，且这些病变最常出现在面部、颈部和躯干，每个部位各有10匹马出现。9匹马四肢受累，7匹马出现瘙痒，4匹马有脓疱。临床症状大多与先前报告中描述的相符，但疼痛症状并非突出特征。6匹马中有4匹在细胞学上鉴定出棘层松解细胞。
