在一匹幼驹中使用金化合物治疗落叶型天疱疮。
Use of a gold compound for the treatment of pemphigus foliaceus in a foal.
作者信息
Power H T, McEvoy E O, Manning T O
出版信息
J Am Vet Med Assoc. 1982 Feb 15;180(4):400-3.
PMID:6800993
Abstract
A 4-month-old foal was examined because of generalized exfoliative dermatitis, with thick scales, extensive crusting, and oozing of serum. A diagnosis of pemphigus foliaceus was made by histologic and immunopathologic examinations of skin biopsy specimens. The foal was treated with a gold compound, aurothioglucose (1 mg/kg once weekly for 14 weeks). For the initial 5 weeks, high-dose glucocorticoid treatments also was used. The skin disorder resolved entirely after 12 weeks of treatment.
摘要
一匹4个月大的马驹因全身性剥脱性皮炎接受检查，其皮肤有厚厚的鳞屑、广泛的结痂以及血清渗出。通过对皮肤活检标本进行组织学和免疫病理学检查，诊断为落叶型天疱疮。该马驹接受了金化合物硫代葡萄糖金的治疗（每周1次，每次1 mg/kg，共14周）。在最初的5周内，还使用了高剂量的糖皮质激素治疗。治疗12周后，皮肤疾病完全痊愈。
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