Ji Jianguang, Hemminki Kari
Department of Bioscience at Novum, Karolinska Institutet, Huddinge, Sweden.
Ann Epidemiol. 2006 May;16(5):370-6. doi: 10.1016/j.annepidem.2005.09.002. Epub 2005 Oct 24.
The aim of the study is to investigate associations between socioeconomic and occupational factors and lymphoproliferative (LP) diseases.
We performed a follow-up study on the economically active Swedish population, based on the Swedish Family-Cancer Database. Standardized incidence ratios and 95% confidence intervals were calculated in different social classes and occupations.
An increased risk for LP diseases was observed for physicians, plumbers, chemical process workers, and food manufacture workers among men and shoe and leather workers, mechanics, iron and metalware workers, and launderers and dry cleaners among women.
Results suggest that socioeconomic and occupational factors have a minor effect on risk for LP diseases. Exposure to organic solvents may increase the risk for some LP diseases, although inconsistencies of findings between subcohorts do not rule out spurious associations.
本研究旨在调查社会经济和职业因素与淋巴增生性(LP)疾病之间的关联。
我们基于瑞典家庭癌症数据库,对瑞典有经济活动的人群进行了一项随访研究。计算了不同社会阶层和职业的标准化发病率及95%置信区间。
在男性中,观察到医生、水管工、化学工艺工人和食品制造工人患LP疾病的风险增加;在女性中,鞋类和皮革工人、机械师、钢铁和金属制品工人以及洗衣工和干洗工患LP疾病的风险增加。
结果表明,社会经济和职业因素对LP疾病风险的影响较小。接触有机溶剂可能会增加某些LP疾病的风险,尽管亚队列之间研究结果的不一致并不能排除虚假关联。