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[局限性前列腺癌早期检测与分期的创新理念]

[Innovative concepts in early cancer detection and staging of localized prostate cancer].

作者信息

Rinnab L, Küfer R, Hautmann R E, Volkmer B G, Straub M, Blumstein N M, Gottfried H W

机构信息

Abteilung Urologie und Kinderurologie, Universitätsklinikum, Ulm.

出版信息

Urologe A. 2005 Nov;44(11):1262, 1264-6, 1268-70, 1272-5. doi: 10.1007/s00120-005-0931-4.

Abstract

Prostate cancer is the most common malignancy in males. Men aged 50 years and older are recommended to undergo an annual digital rectal examination (DRE) and determination of prostate-specific antigen (PSA) in serum for early detection. Fortunately, disease-specific mortality continues to decline as a result of advances in screening, staging, and patient awareness. However, about 30% of men with a clinically organ-confined disease show evidence of extracapsular extension or seminal vesicle invasion on pathological analysis. Consequently, there is a need for more accurate diagnostic tools for planning tailored treatment. A variety of modern imaging techniques has been implemented in an attempt to obtain more precise staging, thereby allowing for more detailed counseling, and instituting optimum therapy. This review highlights developments in prostate cancer imaging that may improve staging and treatment planning for prostate cancer patients.

摘要

前列腺癌是男性中最常见的恶性肿瘤。建议50岁及以上的男性每年进行一次直肠指检(DRE)并测定血清前列腺特异性抗原(PSA)以进行早期检测。幸运的是,由于筛查、分期和患者意识的进步,疾病特异性死亡率持续下降。然而,约30%临床诊断为器官局限性疾病的男性在病理分析中显示有包膜外侵犯或精囊侵犯的证据。因此,需要更准确的诊断工具来规划个性化治疗。为了获得更精确的分期,从而能够进行更详细的咨询并制定最佳治疗方案,已经采用了多种现代成像技术。本综述重点介绍了前列腺癌成像方面的进展,这些进展可能会改善前列腺癌患者的分期和治疗规划。

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