通过核磁共振、X射线和半经验方法（PM3与AM1）对核苷进行构象比较分析。
Comparative conformational analysis of nucleosides by NMR, X-ray, and semi-empirical (PM3 VS. AM1) methods.
作者信息
Mikhailopulo Igor A, Sokolov Yuri A, He Junlin, Chittepu Padmaja, Rosemeyer Helmut, Seela Frank
机构信息
Department of Pharmaceutical Chemistry, University of Kuopio, P.O. Box 1627, Kuopio 70211, Finland.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):701-5. doi: 10.1081/ncn-200060278.
PMID:16248018
Abstract
The 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl ortho-aza-purine and -pyrimidine nucleosides manifest an unusually rigid sugar N conformation in solution.
摘要
2'-脱氧-2'-氟-β-D-阿拉伯呋喃糖基邻氮嘌呤和嘧啶核苷在溶液中呈现出异常刚性的糖N构象。
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