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达英-35联合加味右归丸治疗多囊卵巢综合征的临床研究

[Clinical research on combined therapy of diane-35 with modified yougui pill on polycystic ovarian syndrome].

作者信息

Chen Li-sheng, Zhou Jin-tang

机构信息

Fujian Provincial People's Hospital, Fuzhou.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Sep;25(9):794-6.

PMID:16248240
Abstract

OBJECTIVE

To investigate the clinical efficacy of integrative traditional Chinese and Western medicine on polycystic ovarian syndrome (PCOC).

METHODS

Sixty-three patients with polycystic ovarian syndrome were randomly allocated into 2 groups, 31 patients orally administered with diane-35 in the Western medicine group (WMG) and 32 patients treated with conventional controlled medicine plus modified Yougui Pill in the integrative medicine group (IMG). Changes of relevant hormones and clinical syndromes in patients were detected before treatment, after 3 cyclic treatment and at the 6th cycle after treatment.

RESULTS

The levels of relevant hormones and the indexes of B-ultrasonic were obviously improved after treatment in the two groups. But 6 cycles after treatment, these changes restored to the baseline as those before treatment in WMG, while maintained in IMG (P < 0.01). What's more, the normalization of menstruation, ovulation and pregnancy rate in IMG were significantly higher than those in WMG (P < 0.01).

CONCLUSION

Diane-35 combined with modified yougui pill in treating polycystic ovarian syndrome not only shows marked short-term effect, but could consolidate the curative effect.

摘要

目的

探讨中西医结合治疗多囊卵巢综合征(PCOC)的临床疗效。

方法

将63例多囊卵巢综合征患者随机分为2组,西药组(WMG)31例口服达英-35,中西医结合组(IMG)32例采用传统对照药物加用右归丸加减治疗。于治疗前、3个周期治疗后及治疗后第6周期检测患者相关激素及临床症状的变化。

结果

两组治疗后相关激素水平及B超指标均明显改善。但治疗6个周期后,西药组上述变化恢复至治疗前基线水平,而中西医结合组则维持改善状态(P<0.01)。此外,中西医结合组月经、排卵恢复正常率及妊娠率显著高于西药组(P<0.01)。

结论

达英-35联合右归丸加减治疗多囊卵巢综合征不仅近期疗效显著,而且能巩固疗效。

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