精神病作为双相情感障碍锂盐维持治疗反应的预测指标。

Psychosis as a predictor of response to lithium maintenance treatment in bipolar affective disorder.

作者信息

Rosenthal N E, Rosenthal L N, Stallone F, Fleiss J, Dunner D L, Fieve R R

出版信息

J Affect Disord. 1979 Dec;1(4):237-45. doi: 10.1016/0165-0327(79)90010-7.

Abstract

Sixty-six bipolar I lithium clinic patients were studied for a history of psychotic symptoms at some time during the course of their illness. Agreement between different sources of information was calculated, and the patient population was divided into psychotic and non-psychotic subgroups. Probability of remaining well on lithium for the different subgroups was analyzed by the life table method. Psychosis during mania appeared to be associated with especially good early lithium prophylaxis.

摘要

对66例双相I型锂盐门诊患者在其病程中的某个时间点的精神病症状史进行了研究。计算了不同信息来源之间的一致性，并将患者群体分为精神病性和非精神病性亚组。采用生命表法分析了不同亚组患者继续使用锂盐保持良好状态的概率。躁狂发作时的精神病似乎与特别良好的早期锂盐预防有关。