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双相躁狂症中精神病性特征的患病率及描述

Prevalence and description of psychotic features in bipolar mania.

作者信息

Dunayevich E, Keck P E

机构信息

Clinical Psychobiology Program, Department of Psychiatry, University of Cincinnati, PO Box 670559, Cincinnati, OH 45267-0559, USA.

出版信息

Curr Psychiatry Rep. 2000 Aug;2(4):286-90. doi: 10.1007/s11920-000-0069-4.

Abstract

Psychotic symptoms are common in both the manic and depressive phases of bipolar disorder. More than half of patients with bipolar disorder will experience psychotic symptoms in their lifetime. Grandiose delusions are the most common type of psychotic symptom, but any kind of psychotic symptom, including thought disorder, hallucinations, mood-incongruent psychotic symptoms, and catatonia can present as part of a manic episode. Psychotic symptoms suggest poor prognosis when they occur in the absence of affective symptoms. However, psychotic symptoms can mask affective symptoms and make the distinction between manic-depressive illness and other psychiatric disorders difficult, especially in minorities. Careful assessment of prior psychiatric history, family history, and treatment response can aid in the differentiation of affective disorders with psychotic features from psychotic disorders.

摘要

精神病性症状在双相情感障碍的躁狂和抑郁发作期均很常见。超过半数的双相情感障碍患者一生中会出现精神病性症状。夸大妄想是最常见的精神病性症状类型,但任何一种精神病性症状,包括思维障碍、幻觉、心境不协调性精神病性症状及紧张症,都可能作为躁狂发作的一部分出现。当精神病性症状在无情感症状的情况下出现时,提示预后不良。然而,精神病性症状可能会掩盖情感症状,使得区分躁狂抑郁性疾病和其他精神障碍变得困难,尤其是在少数群体中。仔细评估既往精神病史、家族史及治疗反应有助于鉴别伴有精神病性特征的情感障碍和精神病性障碍。

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