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个体贫困、血糖控制与糖尿病并发症之间的关联:EPICES评分

Association among individual deprivation, glycemic control, and diabetes complications: the EPICES score.

作者信息

Bihan Hélène, Laurent Silvana, Sass Catherine, Nguyen Gérard, Huot Caroline, Moulin Jean Jacques, Guegen René, Le Toumelin Philippe, Le Clésiau Hervé, La Rosa Emilio, Reach Gérard, Cohen Régis

机构信息

Université Paris XIII (CRNH) et Services de Médicine Interne et d'Endocrinologie, Hôpital Avicenne, 93009 Bobigny Cedex, France.

出版信息

Diabetes Care. 2005 Nov;28(11):2680-5. doi: 10.2337/diacare.28.11.2680.

Abstract

OBJECTIVE

Previous studies have related poor glycemic control and/or some diabetes complications to low socioeconomic status. Some aspects of socioeconomic status have not been assessed in these studies. In the present study, we used an individual index of deprivation, the Evaluation de la Précarité et des Inégalités de santé dans les Centres d'Examens de Santé (Evaluation of Precarity and Inequalities in Health Examination Centers [EPICES]) score, to determine the relationship among glycemic control, diabetes complications, and individual conditions of deprivation.

RESEARCH DESIGN AND METHODS

We conducted a cross-sectional prevalence study in 135 consecutive diabetic patients (age 59.41 +/- 13.2 years [mean +/- SD]) admitted in the hospitalization unit of a French endocrine department. Individual deprivation was assessed by the EPICES score, calculated from 11 socioeconomic questions. Glycemic control, lipid levels, blood pressure, retinopathy, neuropathy, and nephropathy were assessed.

RESULTS

HbA(1c) level was significantly correlated with the EPICES score (r = 0.366, P < 0.001). The more deprived patients were more likely than the less deprived patients to have poor glycemic control (beta = 1.984 [SE 0.477], P < 0.001), neuropathy (odds ratio 2.39 [95% CI 1.05-5.43], P = 0.037), retinopathy (3.66 [1.39-9.64], P = 0.009), and being less often admitted for 1-day hospitalization (0.32 [0.14-0.74], P = 0.008). No significant relationship was observed with either nephropathy or cardiovascular risk factors.

CONCLUSIONS

Deprivation status is associated with poor metabolic control and more frequent microvascular complications, i.e., retinopathy and neuropathy. The medical and economic burden of deprived patients is high.

摘要

目的

既往研究已将血糖控制不佳和/或某些糖尿病并发症与社会经济地位低下联系起来。这些研究尚未评估社会经济地位的某些方面。在本研究中,我们使用了一个个体贫困指数,即健康检查中心的脆弱性与健康不平等评估(EPICES)评分,来确定血糖控制、糖尿病并发症和个体贫困状况之间的关系。

研究设计与方法

我们对法国一个内分泌科住院部收治的135例连续糖尿病患者(年龄59.41±13.2岁[均值±标准差])进行了一项横断面患病率研究。通过由11个社会经济问题计算得出的EPICES评分来评估个体贫困状况。评估血糖控制、血脂水平、血压、视网膜病变、神经病变和肾病。

结果

糖化血红蛋白(HbA1c)水平与EPICES评分显著相关(r = 0.366,P < 0.001)。贫困程度较高的患者比贫困程度较低的患者更有可能血糖控制不佳(β = 1.984[标准误0.477],P < 0.001)、发生神经病变(比值比2.39[95%置信区间1.05 - 5.43],P = 0.037)、视网膜病变(3.66[1.39 - 9.64],P = 0.009),且较少因一日住院而入院(0.32[0.14 - 0.74],P = 0.008)。未观察到与肾病或心血管危险因素有显著关系。

结论

贫困状况与代谢控制不佳及更频繁的微血管并发症(即视网膜病变和神经病变)相关。贫困患者的医疗和经济负担很重。

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