在人类粪便菌群中，糖肽抗性基因vanB、vanD和vanG的高流行率与肠球菌无关。
High prevalence of glycopeptide resistance genes vanB, vanD, and vanG not associated with enterococci in human fecal flora.
作者信息
Domingo M-C, Huletsky A, Giroux R, Boissinot K, Picard F J, Lebel P, Ferraro M J, Bergeron M G
机构信息
Centre de Recherche en Infectiologie de l'Université Laval, CHUQ (Pavillon CHUL), 2705 boul. Laurier, Sainte-Foy, Québec, G1V 4G2, Canada.
出版信息
Antimicrob Agents Chemother. 2005 Nov;49(11):4784-6. doi: 10.1128/AAC.49.11.4784-4786.2005.
Abstract
The presence of Enterococcus-associated vancomycin resistance genes vanA, vanB, vanD, vanE, and vanG in rectal swabs was investigated in two hospitals using PCR. All vanA genes detected were associated with vancomycin-resistant enterococci (VRE), whereas VRE-associated vanB genes were detected in only one hospital (4.7%). However, in both hospitals, high prevalences of vanB (6.2 and 2.3%), vanD (43.8 and 26.7%), and vanG (10.5 and 6.9%) genes not associated with enterococci were found.
摘要
使用聚合酶链反应（PCR）在两家医院对直肠拭子中与肠球菌相关的万古霉素耐药基因vanA、vanB、vanD、vanE和vanG的存在情况进行了调查。所有检测到的vanA基因均与耐万古霉素肠球菌（VRE）相关，而仅在一家医院检测到与VRE相关的vanB基因（4.7%）。然而，在两家医院中，均发现了高比例的与肠球菌无关的vanB基因（6.2%和2.3%）、vanD基因（43.8%和26.7%）和vanG基因（10.5%和6.9%）。
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