青霉素与头孢地尼在根除A组链球菌和扁桃体菌群方面的疗效比较
Efficacy of penicillin versus cefdinir in eradication of group A streptococci and tonsillar flora.
作者信息
Brook Itzhak, Foote Perry A
机构信息
Department of Pediatrics, Georgetown University School of Medicine, Washington DC, USA.
出版信息
Antimicrob Agents Chemother. 2005 Nov;49(11):4787-8. doi: 10.1128/AAC.49.11.4787-4788.2005.
Abstract
Core tonsillar cultures were obtained from 40 children with recurrent tonsillitis treated with either penicillin or cefdinir. Group A beta-hemolytic streptococci were isolated from 11 penicillin- and 3 cefdinir-treated (P < 0.001) patients. beta-Lactamase producers were recovered from 17 penicillin- and 3 cefdinir-treated (P < 0.01) patients. Inhibiting alpha-hemolytic streptococci were isolated less often from penicillin-treated patients than from cefdinir-treated patients.
摘要
从40例接受青霉素或头孢地尼治疗的复发性扁桃体炎患儿中获取扁桃体核心培养物。在接受青霉素治疗的11例和头孢地尼治疗的3例患者中分离出A组β溶血性链球菌（P<0.001）。在接受青霉素治疗的17例和头孢地尼治疗的3例患者中分离出β-内酰胺酶产生菌（P<0.01）。与头孢地尼治疗的患者相比，青霉素治疗的患者中α溶血性链球菌的分离频率较低。
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