阿奇霉素质量分布对眼部沙眼衣原体抗生素敏感性的影响。
Impact of mass distribution of azithromycin on the antibiotic susceptibilities of ocular Chlamydia trachomatis.
作者信息
Solomon Anthony W, Mohammed Zeena, Massae Patrick A, Shao John F, Foster Allen, Mabey David C W, Peeling Rosanna W
机构信息
Clinical Research Unit, London School of Hygiene & Tropical Medicine, Keppel St., London WC1E 7HT, United Kingdom.
出版信息
Antimicrob Agents Chemother. 2005 Nov;49(11):4804-6. doi: 10.1128/AAC.49.11.4804-4806.2005.
Abstract
In a community of Tanzania where trachoma is endemic, we cultured conjunctival swabs from all residents who had active trachoma and were PCR positive for ocular Chlamydia trachomatis, both before (43 isolates) and 2 months after (9 isolates) mass antibiotic treatment. No clinically or programmatically significant increase in azithromycin or tetracycline resistance was observed.
摘要
在坦桑尼亚沙眼流行的一个社区，我们对所有患有活动性沙眼且眼部沙眼衣原体PCR检测呈阳性的居民的结膜拭子进行培养，分别在大规模抗生素治疗前（43株分离株）和治疗后2个月（9株分离株）进行。未观察到阿奇霉素或四环素耐药性在临床或项目方面有显著增加。
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