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比较橡皮圈套扎术与痔切除术的随机试验的系统评价

Systematic review of randomized trials comparing rubber band ligation with excisional haemorrhoidectomy.

作者信息

Shanmugam V, Thaha M A, Rabindranath K S, Campbell K L, Steele R J C, Loudon M A

机构信息

Department of Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.

出版信息

Br J Surg. 2005 Dec;92(12):1481-7. doi: 10.1002/bjs.5185.

Abstract

BACKGROUND AND METHOD

This review compares the two most popular treatments for haemorrhoids, namely rubber band ligation (RBL) and excisional haemorrhoidectomy. Randomized trials were identified from the major electronic databases. Symptom control, retreatment, postoperative pain, complications, time off work and patient satisfaction were assessed. Relative risk (RR) and weighted mean difference with 95 per cent confidence interval (c.i.) were estimated using a random-effects model for dichotomous and continuous outcomes respectively.

RESULTS

Three trials met the inclusion criteria and all were of poor methodological quality. Complete remission of haemorrhoidal symptoms was better after haemorrhoidectomy (RR 1.68 (95 per cent c.i 1.00 to 2.83)). There was significant heterogeneity between the studies (I(2) = 90.5 per cent; P < 0.001). Fewer patients required retreatment after haemorrhoidectomy (RR 0.20 (95 per cent c.i 0.09 to 0.40)), but anal stenosis, postoperative haemorrhage and incontinence to flatus were more common with this operation.

CONCLUSIONS

Haemorrhoidectomy produced better long-term symptom control in patients with grade III haemorrhoids, but was associated with more postoperative complications than RBL.

摘要

背景与方法

本综述比较了两种最常用的痔疮治疗方法,即橡皮圈套扎术(RBL)和痔切除术。从主要电子数据库中检索随机试验。评估症状控制、再次治疗、术后疼痛、并发症、误工时间和患者满意度。分别使用随机效应模型对二分法和连续结果估计相对风险(RR)和95%置信区间(c.i.)的加权平均差。

结果

三项试验符合纳入标准,且所有试验的方法学质量均较差。痔切除术后痔症状的完全缓解情况更好(RR 1.68(95% c.i. 1.00至2.83))。各研究之间存在显著异质性(I² = 90.5%;P < 0.001)。痔切除术后需要再次治疗的患者较少(RR 0.20(95% c.i. 0.09至0.40)),但该手术中肛门狭窄、术后出血和气体失禁更为常见。

结论

痔切除术在III度痔疮患者中产生了更好的长期症状控制,但与橡皮圈套扎术相比,术后并发症更多。

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