Etsuda Hirokuni, Miyamoto Akira, Nakajima Yutaka, Hakamata Naohiro, Yamauchi Yasutaka, Akita Takako, Fukuda Masahiro
Cardiac Division, Kawasaki Saiwai Hospital, Kawasaki.
J Cardiol. 2005 Oct;46(4):155-60.
A 62-year-old diabetic man was admitted to our hospital because of acute myocardial infarction. Emergent coronary angiography showed multiple thromboembolic occlusions in the distal circumflex and anterior descending arteries. For the first 2 weeks of hospitalization, he suffered multiple organ manifestations including the gastrointestinal, central nervous, renal and respiratory systems. The anticardiolipin beta2GP1 complex antibody titer on the 15th day was as high as 27.2 U/l (normal value < 3.5). These clinical manifestations and laboratory findings suggested catastrophic antiphospholipid antibody syndrome. He was discharged on the 83rd day with anticoagulant therapy and regular hemodialysis. Acute myocardial infarction is rare as the initial manifestation of catastrophic antiphospholipid antibody syndrome.
一名62岁的糖尿病男性因急性心肌梗死入住我院。急诊冠状动脉造影显示回旋支远端和前降支多处血栓栓塞性闭塞。住院的前两周，他出现了包括胃肠道、中枢神经、肾脏和呼吸系统在内的多器官表现。第15天抗心磷脂β2GP1复合物抗体滴度高达27.2 U/l（正常值<3.5）。这些临床表现和实验室检查结果提示灾难性抗磷脂抗体综合征。他在第83天出院，接受抗凝治疗并定期进行血液透析。急性心肌梗死作为灾难性抗磷脂抗体综合征的初始表现较为罕见。
