Boitano Louis J, Benditt Joshua O
Department of Respiratory Care, Division of Pulmonary and Critical Care Medicine, and the Northwest Assisted Breathing Center, University of Washington Medical Center, Seattle, Washington 98195, USA.
Respir Care. 2005 Nov;50(11):1457-61.
Open-circuit mouthpiece ventilation (MPV) is a form of noninvasive ventilation that can be used to provide portable daytime ventilatory support for neuromuscular patients with chronic respiratory failure. MPV has been reported to reduce the risk of respiratory infection due to tracheostomy, and to improve cough and voice function and patient quality of life. Despite these potential benefits, mouthpiece ventilation is not widely used. This may be due in part to the fact that little information is available as to which ventilators can support this application.
To determine which volume-cycled portable home ventilators currently available in the United States will support MPV, and what peak inspiratory flow rates create adequate circuit pressure to prevent low-pressure alarming.
We used a commercially available MPV breathing circuit with a set tidal volume range of 500\N1,000 mL with each of 8 ventilators currently available in the United States.
Six of the 8 ventilators supported MPV: Respironics Lifecare PLV-100 and PLV Continuum, Mallinckrodt Achieva PSO2, Pulmonetics LTV800, Newport HT50, and Uni-Vent Eagle 754.
开放式口含管通气（MPV）是一种无创通气形式，可用于为患有慢性呼吸衰竭的神经肌肉疾病患者提供便携式日间通气支持。据报道，MPV可降低气管切开术导致的呼吸道感染风险，并改善咳嗽和声音功能以及患者生活质量。尽管有这些潜在益处，但口含管通气并未得到广泛应用。这可能部分是由于关于哪些呼吸机可支持这种应用的信息很少。
确定美国目前可用的哪些容量控制便携式家用呼吸机可支持MPV，以及哪些吸气峰流速可产生足够的回路压力以防止低压报警。
我们使用了一种市售的MPV呼吸回路，其潮气量设定范围为500至1000毫升，与美国目前可用的8台呼吸机中的每一台配合使用。
8台呼吸机中有6台支持MPV：瑞思迈Lifecare PLV - 100和PLV Continuum、马利克罗斯特Achieva PSO2、普美康LTV800、纽波特HT50以及优利康Eagle 754。
