非精神病性求助者的类精神病体验：与痛苦、抑郁及残疾的关联
Psychotic-like experiences in nonpsychotic help-seekers: associations with distress, depression, and disability.
作者信息
Yung Alison R, Buckby Joe A, Cotton Sue M, Cosgrave Elizabeth M, Killackey Eoin J, Stanford Carrie, Godfrey Katherine, McGorry Patrick D
机构信息
ORYGEN Research Centre, Parkville, Victoria, Australia.
出版信息
Schizophr Bull. 2006 Apr;32(2):352-9. doi: 10.1093/schbul/sbj018. Epub 2005 Oct 27.
Psychotic-like experiences (PLEs) increase the risk of schizophrenia and other psychotic disorders yet are common in the community. Some PLEs, such as those associated with depression, distress, and poor functioning, may confer increased risk. The aim of this study is to determine the prevalence of PLEs in a nonpsychotic clinical sample and to investigate whether any subtypes of PLEs are associated with the above factors. Consecutive referrals to a youth psychiatric service (N = 140) were assessed to measure PLEs, depression, and functioning. PLE data were factor analyzed, and the associations of psychotic subtypes and distress, depression, and disability were analyzed. Three subtypes of PLEs were identified: Bizarre Experiences, Persecutory Ideas, and Magical Thinking. Bizarre Experiences and Persecutory Ideas were associated with distress, depression, and poor functioning. Magical Thinking was not, unless accompanied by distress. Bizarre Experiences and Persecutory Ideas may be more malignant forms of psychotic symptoms, as they are associated with current disability, and may confer increased risk of development of full-blown psychotic disorder.
类精神病体验（PLEs）会增加患精神分裂症和其他精神障碍的风险，然而在社区中却很常见。一些PLEs，比如那些与抑郁、痛苦和功能不良相关的体验，可能会带来更高的风险。本研究的目的是确定非精神病性临床样本中PLEs的患病率，并调查PLEs的任何亚型是否与上述因素相关。对连续转介至青少年精神科服务机构的患者（N = 140）进行评估，以测量PLEs、抑郁和功能状况。对PLE数据进行因子分析，并分析精神病性亚型与痛苦、抑郁和残疾之间的关联。确定了PLEs的三种亚型：怪异体验、被害观念和神奇思维。怪异体验和被害观念与痛苦、抑郁和功能不良相关。神奇思维则不然，除非伴有痛苦。怪异体验和被害观念可能是更具危害性的精神病性症状形式，因为它们与当前的残疾相关，并且可能会增加发展为全面精神病性障碍的风险。
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