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青少年社区样本中的类精神病体验:对精神病连续体模型及精神分裂症预测的启示

Psychotic-like experiences in a community sample of adolescents: implications for the continuum model of psychosis and prediction of schizophrenia.

作者信息

Yung Alison R, Nelson Barnaby, Baker Kathryn, Buckby Joe A, Baksheev Gennady, Cosgrave Elizabeth M

机构信息

Orygen Youth Health Research Centre and Department of Psychiatry, University of Melbourne, Parkville, Vic, Australia.

出版信息

Aust N Z J Psychiatry. 2009 Feb;43(2):118-28. doi: 10.1080/00048670802607188.

Abstract

OBJECTIVE

Studies conducted in community samples suggest that psychotic-like experiences are common in the general population, leading to suggestions that they are either variations of normal personality or are different expressions of underlying vulnerability to psychotic disorder. Different types of psychotic symptoms may exist, some being normal variants and some having implications for mental health and functioning. The aim of the present study was to determine if different subtypes of psychotic-like experiences could be identified in a community sample of adolescents and to investigate if particular subtypes were more likely to be associated with psychosocial difficulties, that is, distress, depression and poor functioning, than other subtypes.

METHOD

Eight hundred and seventy-five Year 10 students from 34 schools participated in a cross-sectional survey that measured psychotic-like experiences using the Community Assessment of Psychic Experiences; depression using the Centre for Epidemiologic Studies Depression Scale; and psychosocial functioning using the Revised Multidimensional Assessment of Functioning Scale. Factor analysis was conducted to identify any subtypes of psychotic experiences.

RESULTS

Four subtypes of psychotic-like experiences were identified: Bizarre Experiences, Perceptual Abnormalities, Persecutory Ideas, and Magical Thinking. Intermittent, infrequent psychotic experiences were common, but frequent experiences were not. Bizarre Experiences, Perceptual Abnormalities and Persecutory Ideas were strongly associated with distress, depression and poor functioning. Magical Thinking was only weakly associated with these variables. Overall these findings may suggest that infrequent psychotic-like experiences are unlikely to be a specific risk factor for onset of a psychotic disorder in community samples.

CONCLUSIONS

Given that the different subtypes had varying associations with current difficulties it is suggested that not all subtypes confer the same risk for onset of psychotic disorder and poor outcome. Bizarre Experiences, Perceptual Abnormalities and Persecutory Ideas may represent expressions of underlying vulnerability to psychotic disorder, but Magical Thinking may be a normal personality variant.

摘要

目的

在社区样本中进行的研究表明,类精神病体验在普通人群中很常见,这引发了关于它们要么是正常人格变异,要么是精神病性障碍潜在易感性的不同表现形式的观点。可能存在不同类型的精神病症状,有些是正常变异,有些则对心理健康和功能有影响。本研究的目的是确定在青少年社区样本中是否可以识别出类精神病体验的不同亚型,并调查特定亚型是否比其他亚型更有可能与心理社会困难相关,即痛苦、抑郁和功能不良。

方法

来自34所学校的875名10年级学生参与了一项横断面调查,该调查使用《精神体验社区评估》来测量类精神病体验;使用《流行病学研究中心抑郁量表》来测量抑郁;使用《修订的多维功能评估量表》来测量心理社会功能。进行因子分析以识别精神病体验的任何亚型。

结果

识别出类精神病体验的四种亚型:怪异体验、感知异常、被害观念和神奇思维。间歇性、不频繁的精神病体验很常见,但频繁体验并不常见。怪异体验、感知异常和被害观念与痛苦、抑郁和功能不良密切相关。神奇思维与这些变量的关联较弱。总体而言,这些发现可能表明,在社区样本中,不频繁的类精神病体验不太可能是精神病性障碍发病的特定危险因素。

结论

鉴于不同亚型与当前困难有不同的关联,建议并非所有亚型都具有相同的精神病性障碍发病风险和不良后果风险。怪异体验、感知异常和被害观念可能代表了对精神病性障碍潜在易感性的表现,但神奇思维可能是一种正常人格变异。

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