Nielsen Ulrik B, Schoeberl Brigit
Merrimack Pharmaceuticals Inc, Cambridge, MA 02142, USA.
IDrugs. 2005 Oct;8(10):822-6.
Computational biology is impacting drug design and has the potential to revolutionize the drug development process. Here, we describe how data-driven computational models can optimize the design of targeted therapeutics to yield improved safety and efficacy. We propose that, in the future, this approach will improve drug discovery, clinical development, diagnosis and treatment.
计算生物学正在影响药物设计，并有潜力彻底改变药物开发过程。在此，我们描述了数据驱动的计算模型如何优化靶向治疗药物的设计，以提高安全性和疗效。我们认为，在未来，这种方法将改善药物发现、临床开发、诊断和治疗。
