Fischbach W
Medizinische Poliklinik, Universität Würzburg.
Leber Magen Darm. 1992 May;22(3):96-101.
This article summarizes the data concerning cancer risk in chronic inflammatory bowel disease. Cancer risk of ulcerative colitis and Crohn's disease is highly dependent on the duration of the disease, extent of bowel inflammation, and probably also of the age at onset of the disease. Cancer development follows the dysplasia-carcinoma-sequence. Diagnosis of premalignant changes is the basis for follow-up studies in ulcerative colitis as suggested here.
本文总结了有关慢性炎症性肠病癌症风险的数据。溃疡性结肠炎和克罗恩病的癌症风险高度依赖于疾病持续时间、肠道炎症程度，可能还与疾病发病年龄有关。癌症发展遵循发育异常-癌序列。如本文所建议，癌前病变的诊断是溃疡性结肠炎随访研究的基础。
