一种钴铬冠状动脉支架合金的顺应性——COVIS试验

Compliance of a cobalt chromium coronary stent alloy--the COVIS trial.

作者信息

Hagemeister Jens, Baer Frank M, Schwinger Robert H G, Höpp Hans W

机构信息

Department of Medicine III, University of Cologne, Kerpener Str, 62, 50924 Cologne, Germany.

出版信息

Curr Control Trials Cardiovasc Med. 2005 Oct 28;6(1):17. doi: 10.1186/1468-6708-6-17.

DOI:10.1186/1468-6708-6-17

PMID:16255780

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1283148/

Abstract

BACKGROUND

Cobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions. There are, however, no reliable data about the characteristics of unfolding and visibility of this stent alloy in vivo. The aim of this study is to compare cobalt chromium coronary stents with conventional stainless steel stents using intracoronary ultrasound.

METHODS

Twenty de novo native coronary stenoses < or = 20 mm in length (target vessel reference diameter > or = 2.5 and < or = 4.0 mm) received under sequential intracoronary ultrasound either a cobalt chromium stent (Multi-Link Vision; n = 10) or a stainless steel stent (Multi-Link Zeta; n = 10).

RESULTS

For optimal unfolding, the cobalt chromium stent requires a higher balloon deployment pressure (13.90 +/- 2.03 atm) than the stainless steel stent (11.50 +/- 2.12 atm). Furthermore, the achieved target vessel diameter of the cobalt chromium stent (Visibility-Index QCA/IVUS Multi-Link Vision 1.13 / Multi-Link Zeta 1.04) is more easily overrated by Quantitative Coronary Analysis.

CONCLUSION

These data indicate that stent material-specific recommendations for optimal implantation pressure and different stent material with an equal design should both be considered in interpreting QCA-analysis.

摘要

背景

钴铬冠状动脉支架在经皮冠状动脉介入治疗中应用越来越广泛。然而，关于这种支架合金在体内展开特性和可视性的可靠数据尚不存在。本研究旨在使用冠状动脉内超声将钴铬冠状动脉支架与传统不锈钢支架进行比较。

方法

20例长度≤20mm的初发原位冠状动脉狭窄（靶血管参考直径≥2.5且≤4.0mm）在冠状动脉内超声引导下序贯接受钴铬支架（Multi-Link Vision；n = 10）或不锈钢支架（Multi-Link Zeta；n = 10）植入。

结果

为实现最佳展开，钴铬支架所需的球囊扩张压力（13.90±2.03个大气压）高于不锈钢支架（11.50±2.12个大气压）。此外，通过定量冠状动脉分析，钴铬支架的靶血管直径（可视性指数QCA/IVUS：Multi-Link Vision为1.13 / Multi-Link Zeta为1.04）更容易被高估。