Graves S R, Banks J, Dwyer B, King G K
Fairfield Infectious Diseases Hospital, Vic.
Med J Aust. 1992 May 4;156(9):650-1. doi: 10.5694/j.1326-5377.1992.tb121464.x.
To present a case of murine (endemic) typhus, the first to be reported within the last 30 years in Australia.
A 17-year-old pregnant woman presented with a viral-like illness and later developed a spotted rash, fever and headache. INVESTIGATION AND OUTCOME: Sera taken on Day 7 and Day 30 of the illness showed seroconversion to Proteus OX19 (Weil-Felix) and to Rickettsia typhi (by immunofluorescence), indicating recent infection with Rickettsia of the typhus group. Her illness was clinically compatible with murine typhus. She responded well to erythromycin and delivered a normal infant at term.
Infection with Rickettsia typhi (murine typhus) still occurs in Australia. It can be diagnosed by means of specific serological tests for rickettsial disease, which are superior to the non-specific Weil-Felix test.
报告一例鼠型(地方性)斑疹伤寒病例,这是澳大利亚近30年来首例报告的此类病例。
一名17岁孕妇起初表现为类似病毒感染的疾病,随后出现斑丘疹、发热和头痛症状。
在发病第7天和第30天采集的血清显示,对变形杆菌OX19(外斐反应)和斑疹伤寒立克次体(通过免疫荧光法)出现血清学转化,表明近期感染了斑疹伤寒群立克次体。其病情在临床上与鼠型斑疹伤寒相符。她对红霉素反应良好,并足月产下一名健康婴儿。
澳大利亚仍有斑疹伤寒立克次体(鼠型斑疹伤寒)感染发生。可通过针对立克次体病的特异性血清学检测进行诊断,这种检测优于非特异性的外斐试验。