斑疹伤寒群立克次体与外斐试验抗原之间抗原相似性的血清学研究。
Serological studies of the antigenic similarity between typhus group rickettsiae and Weil-Felix test antigens.
作者信息
Amano K, Kyohno K, Aoki S, Suto T
机构信息
Central Research Laboratory, Akita University School of Medicine, Japan.
出版信息
Microbiol Immunol. 1995;39(1):63-5. doi: 10.1111/j.1348-0421.1995.tb02169.x.
The sera from two patients with murine typhus reacted with whole cells of Rickettsia prowazekii, R. typhi, and Proteus vulgaris OX19, and with lipopolysaccharides (LPS) from the spotted fever group rickettsia strain TT-118 and P. vulgaris OX19 in the enzyme-linked immunosorbent assay. Sera from these patients reacted with ladder-like bands of LPS from R. prowazekii and R. typhi in the immunoblot, whereas the reactivity of these sera with LPS from P. vulgaris OX19 differed from each other. These results indicate that LPS from the typhus group rickettsiae and P. vulgaris OX19 contain similar epitopes.
两名地方性斑疹伤寒患者的血清在酶联免疫吸附测定中与普氏立克次体、伤寒立克次体和普通变形杆菌OX19的全细胞发生反应，并与斑点热群立克次体菌株TT-118和普通变形杆菌OX19的脂多糖（LPS）发生反应。这些患者的血清在免疫印迹中与普氏立克次体和伤寒立克次体的LPS梯状条带发生反应，而这些血清与普通变形杆菌OX19的LPS的反应性彼此不同。这些结果表明，斑疹伤寒群立克次体的LPS和普通变形杆菌OX19含有相似的表位。
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