使用无细胞下一代测序技术成功检测妊娠中未识别的情况。
Successful Detection of Unrecognized in Pregnancy Using Cell-Free Next-Generation Sequencing.
作者信息
Stafford Irene A, Centeno Fernando H, Al Mohajer Mayar, Parkerson George, Woc-Colburn Laila, Burgos-Lee Angelica Janice, Rac Martha, Dunn James, Muldrew Kenneth
机构信息
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA.
出版信息
Case Rep Obstet Gynecol. 2020 May 26;2020:6767351. doi: 10.1155/2020/6767351. eCollection 2020.
Abstract
Flea-borne (murine) typhus is caused by . Infection in pregnant women can lead to adverse outcomes when diagnosis and treatment is delayed. We describe how next-generation sequencing (NGS) using the Karius® test was used to rapidly diagnose murine typhus in two pregnant women admitted to a large tertiary care center in Houston, Texas, when all initial testing was nondiagnostic.
摘要
蚤传（鼠型）斑疹伤寒是由……引起的。孕妇感染后，若诊断和治疗延误，可能会导致不良后果。我们描述了在德克萨斯州休斯顿一家大型三级医疗中心收治的两名孕妇中，当所有初始检测均无诊断结果时，如何使用Karius®检测的下一代测序（NGS）技术快速诊断鼠型斑疹伤寒。
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