Fayad Fouad, Duet Michèle, Orcel Philippe, Lioté Frédéric
Rheumatology Federation, Viggo Petersen Center, Lariboisière Teaching Hospital, Paris (AP-HP), France.
Joint Bone Spine. 2006 Jan;73(1):109-12. doi: 10.1016/j.jbspin.2005.04.007. Epub 2005 Sep 28.
Systemic sarcoidosis is often diagnosed late. A 37 year-old man from the Antilles was admitted for evaluation of arthralgia, subcutaneous and cutaneous nodules, multiple enlarged lymph nodes, and an epididymal lump. He had been given a diagnosis of epididymal and nodal tuberculosis but had not responded to antitubercular agents. Gallium-67 scintigraphy showed multiple hot spots in the soft tissues, skin, muscles, mediastinum, and lachrymal glands, producing a diffuse dappled pattern. Magnetic resonance imaging of the thighs confirmed the muscular and subcutaneous involvement. Systemic sarcoidosis was diagnosed. Prednisone therapy was promptly effective. We suggest the term "dappled-body sign" or "leopard-man sign" to designate the heretofore undescribed scintigraphic pattern in our patient.
