Isozumi K, Gotoh F, Koto A, Suzuki N, Tsuzuki Y
Department of Neurology, School of Medicine, Keio University, Tokyo, Japan.
Neurosci Lett. 1992 Mar 16;137(1):45-8. doi: 10.1016/0304-3940(92)90294-h.
The vesicles of adventitial autonomic nerve terminals were examined quantitatively under an electron microscope in controlled ultraviolet ray (UV)-irradiated cerebral vessels. Five cats whose basilar arteries were irradiated with UV (UV group) and 5 cats whose basilar arteries were irradiated with visible rays (control group) were compared. Endothelial vacuolation was observed only in the UV group. There was no statistically significant difference in the diameters of the dense-cored vesicles, related to noradrenaline, and clear vesicles, related to acetylcholine, between the two groups. It is concluded that controlled UV irradiation which generates endothelial damage does not affect the vascular adventitia ultrastructurally.
在可控紫外线(UV)照射的脑血管中,通过电子显微镜对血管外膜自主神经末梢的囊泡进行了定量检查。比较了5只基底动脉接受紫外线照射的猫(紫外线组)和5只基底动脉接受可见光照射的猫(对照组)。仅在紫外线组观察到内皮空泡形成。两组之间,与去甲肾上腺素相关的致密核心囊泡和与乙酰胆碱相关的清亮囊泡的直径没有统计学上的显著差异。得出的结论是,产生内皮损伤的可控紫外线照射在超微结构上不会影响血管外膜。