Earle C M, Keogh E J, Ker J K, Cherry D J, Tulloch A G, Lord D J
Reproductive Medicine Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
Paraplegia. 1992 Apr;30(4):273-6. doi: 10.1038/sc.1992.68.
Twenty-two spinal cord injured men (mean age 35.2 years) referred because of impotence were treated with intracavernosal vasoactive agents. Papaverine 2-20 mg, papaverine 40 mg plus phentolamine 0.5 mg or prostaglandin E1 (1-20 micrograms) were used. Nineteen responded and were taught to self administer the medication with varying degrees of assistance from their partners. Fourteen men participated in a postal survey; 12 (86%) continued to use the drugs every 1 to 4 weeks and reported satisfaction with the method. Partner responses were positive in half of the group and when not so it influenced the patients to abandon or reduce the frequency of treatment. Counselling was essential to allay anxiety. Clinical management was not compromised and side effects were minimal. Overall we found this treatment effective, safe and worthwhile.
22名因阳痿前来就诊的脊髓损伤男性（平均年龄35.2岁）接受了海绵体内血管活性药物治疗。使用了2 - 20毫克罂粟碱、40毫克罂粟碱加0.5毫克酚妥拉明或前列腺素E1（1 - 20微克）。19人有反应，并在伴侣不同程度的协助下学会了自行给药。14名男性参与了邮寄调查；12人（86%）每1至4周继续使用这些药物，并报告对该方法满意。一半的伴侣反应积极，若不然则会影响患者放弃或减少治疗频率。咨询对于缓解焦虑至关重要。临床管理未受影响，副作用极小。总体而言，我们发现这种治疗有效、安全且值得。
