Egenvall A, Bonnett B N, Hedhammar A, Olson P
Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Acta Vet Scand. 2005;46(3):121-36. doi: 10.1186/1751-0147-46-121.
This study continues analysis from a companion paper on over 350,000 insured Swedish dogs up to 10 years of age contributing to more than one million dog-years at risk during 1995-2000. The age patterns for total and diagnostic mortality and for general causes of death (trauma, tumour, locomotor, heart and neurological) are presented for numerous breeds. Survival estimates at five, eight and 10 years of age are calculated. Survival to 10 years of age was 75% or more in Labrador and golden retrievers, miniature and toy poodles and miniature dachshunds and lowest in Irish wolfhounds (91% dead by 10 years). Multivariable analysis was used to estimate the relative risk for general and more specific causes of death between breeds accounting for gender and age effects, including two-way interactions. Older females had tumour as a designated cause of death more often than males in most breeds, but not in the Bernese mountain dog. Information presented in this and the companion paper inform our understanding of the population level burden of disease, and support decision-making at the population and individual level about health promotion efforts and treatment and prognosis of disease events.
本研究延续了一篇相关论文的分析，该论文涉及35万多只瑞典参保犬，年龄最大为10岁，在1995 - 2000年期间累积超过100万个犬年的风险。文中呈现了众多犬种的总死亡率和诊断死亡率以及一般死因（创伤、肿瘤、运动系统、心脏和神经方面）的年龄模式。计算了5岁、8岁和10岁时的生存估计值。拉布拉多犬、金毛寻回犬、迷你贵宾犬和玩具贵宾犬以及迷你腊肠犬10岁时的生存率为75%或更高，而爱尔兰猎狼犬的生存率最低（10岁时91%已死亡）。多变量分析用于估计在考虑性别和年龄影响（包括双向交互作用）的情况下，不同犬种之间一般和更具体死因的相对风险。在大多数犬种中，老年雌性比雄性更常将肿瘤列为指定死因，但伯恩山犬并非如此。本论文及相关论文所提供的信息有助于我们了解疾病在种群层面的负担，并支持在种群和个体层面就健康促进措施以及疾病事件的治疗和预后做出决策。
