Hanff G, Dahlin L B, Lundborg G
Department of Hand Surgery, General Hospital, Lund University, Malmö, Sweden.
Scand J Plast Reconstr Surg Hand Surg. 1992;26(1):43-9. doi: 10.3109/02844319209035182.
The medial collateral ligaments in the knee joints of 15 rabbits were replaced with expanded polytetrafluoroethylene (E-PTFE). The joints were not immobilised postoperatively, and their structure and function were evaluated after 12 months. Range of motion was equal in all groups. Stability of the knee joints and breaking strength of the ligaments were similar in the group in which the ligament had been reconstructed and in the sham operated control group (n = 8). The group in which the ligament had been severed and left to heal by formation of scar tissue (n = 7) had significantly reduced joint stability and the breaking strength of the medial collateral ligament was significantly less. The E-PTFE ligaments were well incorporated into the surrounding tissues. There were no adverse tissue reactions and the articular cartilage looked normal both macroscopically and microscopically. These results indicate that E-PTFE might be a useful substitute for damaged ligaments, at least in smaller joints like metacarpophalangeal and interphalangeal joints.
用膨体聚四氟乙烯（E-PTFE）替换15只兔子膝关节的内侧副韧带。术后关节不固定，12个月后评估其结构和功能。所有组的活动范围相同。韧带重建组和假手术对照组（n = 8）的膝关节稳定性和韧带断裂强度相似。韧带切断后靠瘢痕组织愈合的组（n = 7）关节稳定性明显降低，内侧副韧带的断裂强度明显较小。E-PTFE韧带很好地融入周围组织。没有不良组织反应，关节软骨在宏观和微观上看起来都正常。这些结果表明，E-PTFE可能是受损韧带的有用替代品，至少在掌指关节和指间关节等较小关节中是如此。
