Nicolai Joost, Aldenkamp Albert P, Arends Johan, Weber Jacobiene W, Vles Johan S H
Department of Neurology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands.
Epilepsy Behav. 2006 Feb;8(1):56-70. doi: 10.1016/j.yebeh.2005.08.016. Epub 2005 Nov 2.
This review addresses the effects of subclinical localized epileptiform discharges during sleep in children with benign childhood epilepsy with centrotemporal spikes (BCECTS) on cognition and behavior. A diversity of educational deficits, behavioral impairments, language delay, and neuropsychological test results have been reported in children with BCECTS. The occurrence of atypical seizure characteristics seems to be related to language delay, and several atypical EEG characteristics are related to cognitive or behavioral problems. It remains to be shown whether treatment of nocturnal discharges in children with BCECTS is indicated to improve cognitive and behavioral problems.
本综述探讨了伴有中央颞区棘波的儿童良性癫痫（BCECTS）患者睡眠期间亚临床局灶性癫痫样放电对认知和行为的影响。已有报道称，BCECTS患儿存在多种学习缺陷、行为障碍、语言发育迟缓及神经心理学测试结果异常。非典型发作特征的出现似乎与语言发育迟缓有关，一些非典型脑电图特征则与认知或行为问题有关。BCECTS患儿夜间放电的治疗是否有助于改善认知和行为问题，仍有待进一步研究证实。
