Deltour Laëtitia, Quaglino Véronique, Barathon Marion, De Broca Alain, Berquin Patrick
Département Pédiatrie, Neurologie Pédiatrique et Laboratoire Neurosciences Fonctionnelles et Pathologies (CNRS UMR 8160), Hôpital Nord, Amiens, France.
Epileptic Disord. 2007 Dec;9(4):424-31. doi: 10.1684/epd.2007.0127.
The aim of this study was to identify the attentional processes specifically affected in children with benign childhood epilepsy with centrotemporal spikes (BCECTS). The impact of several factors - laterality of discharges, age-at-onset and duration of epilepsy, and medication - on these cognitive functions was also studied. A group of 29 children with BCECTS was evaluated using standardized tests performed in routine clinical practice and specifically designed to assess executive and attentional functions. This group obtained mean scores significantly lower than normative means specifically for tasks involving attention control processes, i.e. cognitive flexibility and inhibitory processes. Neither the epilepsy-related factors that we studied nor the medication appeared to influence performance of these tasks. These data suggest an impact of BCECTS on attentional processes, the most affected being attention control processes that develop late.
本研究的目的是确定伴有中央颞区棘波的儿童良性癫痫（BCECTS）患儿中受到特异性影响的注意力过程。还研究了几个因素——放电的侧别、癫痫发作起始年龄和病程以及药物治疗——对这些认知功能的影响。使用在常规临床实践中进行的标准化测试对一组29例BCECTS患儿进行评估，这些测试是专门设计用于评估执行功能和注意力功能的。该组在涉及注意力控制过程（即认知灵活性和抑制过程）的任务中获得的平均分数显著低于常模均值。我们研究的癫痫相关因素和药物治疗似乎均未影响这些任务的表现。这些数据表明BCECTS对注意力过程有影响，受影响最大的是发育较晚的注意力控制过程。
