Lovisolo Carlo F, Reinstein Dan Z
Department of Ophthalmology and Visual Sciences, San Raffaele Hospital and QuattroElle Eye Center, Milan, Italy, and Department of Ophthalmology, St. Thomas Hospital-Kings College, London, UK.
Surv Ophthalmol. 2005 Nov-Dec;50(6):549-87. doi: 10.1016/j.survophthal.2005.08.011.
An analytical review of the data available in the field of phakic intraocular lens implantation was conducted. Particular attention was paid to the more critical issues of intraocular lens sizing and safety guidelines. A comprehensive, competitive analysis of different implantation sites, intraocular lens model designs, and safety guidelines has been included. Specialized biometry techniques, such as very high frequency ultrasound and Scheimpflug imaging, have been reviewed, and a critical review of commercial claims regarding intraocular lens technologies has been included. Clinical studies of phakic intraocular lenses demonstrate increasing promise for the correction of refractive errors not amenable to mainstream excimer laser refractive surgery. The main issues currently revolve around adequate lens design (VHF ultrasound study suggests that custom-design and sizing may be the most effective and safest approach for every phakic IOL model), because these devices will be required to remain physiologically inert and anatomically compatible with internal ocular structures and relations for several decades. The possibility of safe removing or exchanging the IOL should remain a feasible option over time. It is of utmost importance that we continue to critically evaluate current encouraging short-term outcomes, which are being extrapolated to the longer term by ongoing high resolution imaging and monitoring of the anatomical and functional relations of implanted phakic IOLs.
对有晶状体眼人工晶状体植入领域的现有数据进行了分析综述。特别关注了人工晶状体尺寸确定和安全指南等更关键的问题。纳入了对不同植入部位、人工晶状体模型设计和安全指南的全面、竞争性分析。回顾了专门的生物测量技术，如甚高频超声和Scheimpflug成像，并对有关人工晶状体技术的商业声明进行了批判性审查。有晶状体眼人工晶状体的临床研究表明，对于矫正不适用于主流准分子激光屈光手术的屈光不正，其前景越来越广阔。目前主要问题集中在合适的晶状体设计上（甚高频超声研究表明，定制设计和尺寸确定可能是每种有晶状体眼人工晶状体模型最有效、最安全的方法），因为这些装置需要在几十年内保持生理惰性，并在解剖学上与眼内结构及关系相兼容。随着时间的推移，安全取出或更换人工晶状体的可能性应仍然是一个可行的选择。至关重要的是，我们要继续严格评估当前令人鼓舞的短期结果，这些结果正通过对植入的有晶状体眼人工晶状体的解剖学和功能关系进行持续的高分辨率成像和监测而外推至长期。
