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[原发性输卵管癌的治疗——30例回顾性研究]

[Therapy of primary fallopian tube cancer--a retrospective study of 30 cases].

作者信息

Kaya S, Grillo M, Gent H J

机构信息

Abteilung Frauenheilkunde im Zentrum für operative Medizin I, Christian-Albrechts-Universität und MICHAELIS-Hebammenschule, Kiel.

出版信息

Zentralbl Gynakol. 1992;114(5):254-8.

PMID:1626439
Abstract

Between the years 1968-1988 30 patients with primary carcinoma of the fallopian tube were treated in the Department of Obstetrics and Gynecology of the University of Kiel. In 27 cases the initial treatment consisted of total abdominal hysterectomy and bilateral salpingo-oophorectomy. In 3 cases where the patients had undergone surgical treatment in another hospital a second operation for completion was performed. 2 patients received no further treatment after surgery. Postoperative radiotherapy was given to 20 patients and a combined treatment with radiation and polychemotherapy was implemented in 5 cases. Postoperative treatment in 3 patients was poly-chemotherapy alone. The 5-year-survival rate taking all tumor stages and modes of therapy employed into consideration was 36.7%. In analysing the survival rate for small numbers as directly related to postoperative treatment a 5-year-survival rate for radiotherapy of 35% (7/20) and for radiation therapy plus poly-chemotherapy of 40% (2/5) was found. After operative treatment followed by poly-chemotherapy alone one of three patients survived after 5 years.

摘要

1968年至1988年间,基尔大学妇产科收治了30例原发性输卵管癌患者。27例患者的初始治疗包括全腹子宫切除术和双侧输卵管卵巢切除术。3例患者在其他医院接受过手术治疗,之后进行了二次手术以完善治疗。2例患者术后未接受进一步治疗。20例患者接受了术后放疗,5例患者采用了放疗与多药化疗联合治疗。3例患者术后仅接受多药化疗。综合考虑所有肿瘤分期和治疗方式,5年生存率为36.7%。在分析与术后治疗直接相关的小样本生存率时,发现放疗的5年生存率为35%(7/20),放疗加化疗的5年生存率为40%(2/5)。单纯术后多药化疗后,3例患者中有1例存活5年。

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