Scardina G A, Pizzigatti M E, Messina P
Department of Oral Science, University of Palermo, Palermo, Italy.
J Periodontol. 2005 Nov;76(11):1991-5. doi: 10.1902/jop.2005.76.11.1991.
The aim of this study was to observe the differences in periodontal microcirculation between healthy patients and patients with systemic sclerosis (SSc).
Fifteen healthy patients and 15 patients with SSc were examined. Periodontal capillaroscopy was used to investigate the characteristics of microcirculation. The visibility, course, tortuosity, possible presence of microhemorrhages, average caliber of the capillary loops, and number of visible capillary loops per square millimeter were evaluated for each patient.
The investigation was simple, non-invasive, and repeatable for each patient. In patients with SSc, it was possible to observe a reduced number of capillaries and a greater capillary diameter and tortuosity.
Capillary alterations in patients with SSc are not limited to the nailfold bed but also occur in periodontal mucosa microcirculation. Such evidence could be extremely important in the pathogenesis and treatment of periodontal diseases in patients with SSc.
本研究的目的是观察健康患者与系统性硬化症（SSc）患者牙周微循环的差异。
对15名健康患者和15名SSc患者进行检查。采用牙周毛细血管镜检查来研究微循环的特征。对每位患者的毛细血管环的可见性、走行、迂曲度、是否可能存在微出血、毛细血管环的平均管径以及每平方毫米可见毛细血管环的数量进行评估。
该检查对每位患者而言简单、无创且可重复。在SSc患者中，可以观察到毛细血管数量减少，毛细血管直径和迂曲度增加。
SSc患者的毛细血管改变不仅局限于甲襞床，也发生在牙周黏膜微循环中。这些证据对于SSc患者牙周疾病的发病机制和治疗可能极为重要。
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