精神分裂症中功能总体评定量表得分的主要决定因素：一项欧洲多中心研究
Main determinants of Global Assessment of Functioning score in schizophrenia: a European multicenter study.
作者信息
Gaite Luis, Vázquez-Barquero Jose Luis, Herrán Andres, Thornicroft Graham, Becker Thomas, Sierra-Biddle Dierdre, Ruggeri Mirella, Schene Aarty, Knapp Martin, Vázquez-Bourgon Javier
机构信息
Clinical and Social Psychiatry Research Unit, Department of Psychiatry, University Hospital Marqués de Valdecilla, Santander, Spain.
出版信息
Compr Psychiatry. 2005 Nov-Dec;46(6):440-6. doi: 10.1016/j.comppsych.2005.03.006.
BACKGROUND
The Global Assessment of Functioning (GAF) scale is a measure widely used to assess the outcome of patients with schizophrenia. However, little is known about the importance of clinical and psychosocial variables in determining its final score. The aim of this paper is to identify which factors predict GAF scores of patients with schizophrenia and their variability in 5 different European settings.
METHOD
A representative sample of 404 patients with schizophrenia was assessed with the GAF. A multiple regression analysis was performed to identify predictors of the GAF scores.
RESULTS
Clinical factors are the main determinants of GAF score. However, the analysis also showed that social and functioning factors were also significantly associated with GAF scores. Finally, the study showed the presence of intercenter differences in the factors, mainly in social functioning.
CONCLUSIONS
The GAF is a useful and easy-to-apply measure of global functioning, independent of cross-cultural differences. Clinical factors are the main determinants of its score, although social functioning variables also have a lesser effect.
背景
全球功能评估（GAF）量表是一种广泛用于评估精神分裂症患者预后的工具。然而，对于临床和社会心理变量在决定其最终得分中的重要性，我们知之甚少。本文旨在确定在5种不同的欧洲环境中，哪些因素能够预测精神分裂症患者的GAF得分及其变异性。
方法
使用GAF对404名精神分裂症患者的代表性样本进行评估。进行多元回归分析以确定GAF得分的预测因素。
结果
临床因素是GAF得分的主要决定因素。然而，分析还表明，社会和功能因素也与GAF得分显著相关。最后，研究表明各中心在这些因素上存在差异，主要体现在社会功能方面。
结论
GAF是一种有用且易于应用的整体功能测量工具，不受跨文化差异的影响。临床因素是其得分的主要决定因素，尽管社会功能变量也有较小的影响。
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