Darup J, Bleese N, Kalmar P, Lutz G, Pokar H, Polonius M J
Thorac Cardiovasc Surg. 1979 Aug;27(4):227-30. doi: 10.1055/s-0028-1096250.
In cardiac surgery hemofiltration can be used: 1. to balance fluids during ECC, especially in long-term perfusion; 2. to carry out open heart procedures in patients with terminal renal insufficiency; 3. to treat acute hyperkalemia. The model of the 12.5 by 4.5 cm DIAFILTER TM and the model of operation are described. The compounds of the ultrafiltrate (UF) are identical with that of plasma water. Particles with a molecular weight of less than 50,000 can pass freely across the filtration membrane. The filtration capacity is 100 cc/min UF (Q blood: 300 cc/min, pressure across the membrane 600 mm Hg and hematokrit (Hkt) 25%). The technical details of operation are explained. Its general use as well as its simplicity is demonstrated in 10 patients.
在心脏手术中，血液滤过可用于：1. 在体外循环期间平衡液体，尤其是在长期灌注时；2. 为终末期肾功能不全患者实施心脏直视手术；3. 治疗急性高钾血症。文中描述了直径为12.5×4.5厘米的DIAFILTER TM模型及其操作模式。超滤物（UF）的成分与血浆水相同。分子量小于50,000的颗粒可自由通过滤膜。滤过能力为100 cc/分钟超滤量（血流量：300 cc/分钟，跨膜压力600毫米汞柱，血细胞比容（Hkt）25%）。文中解释了操作的技术细节。在10例患者中展示了其广泛用途及简易性。
