Boldt J, Kling D, von Bormann B, Scheld H H, Hempelmann G
Thorac Cardiovasc Surg. 1987 Jun;35(3):161-5. doi: 10.1055/s-2007-1020221.
Hemofiltration (HF) is an established method for treating patients with impaired renal function and excessive fluid retention. In cardiac surgery fluid accumulation during extracorporeal circulation (ECC) may contribute to postoperative organ dysfunction, leading to severe pulmonary insufficiency. In this study our experiences with hemofiltration installed in the cardiopulmonary bypass are demonstrated in patients with preoperative pulmonary edema, impaired renal function, and long-term ECC, proving its efficacy by measurement of extravascular lung water (EVLW) in the early post-bypass period. EVLW-measurement was performed using the thermal-dye technique with indocyanine green and a microprocessed lung water computer. Our data demonstrate that hemofiltration during ECC is a valuable method for controlling fluid balance. It facilitates the intra- and postoperative management of patients with end-stage renal failure or with preoperative pulmonary edema. HF seems to be helpful by decreasing the risk of complications such as fluid overload, which is demonstrated by measurement of EVLW.
血液滤过（HF）是治疗肾功能受损和液体潴留过多患者的一种既定方法。在心脏手术中，体外循环（ECC）期间的液体蓄积可能导致术后器官功能障碍，进而导致严重的肺功能不全。在本研究中，我们展示了在患有术前肺水肿、肾功能受损和长期ECC的患者中，在心肺转流中安装血液滤过的经验，通过在转流后早期测量血管外肺水（EVLW）来证明其疗效。使用吲哚菁绿热染料技术和微处理肺水计算机进行EVLW测量。我们的数据表明，ECC期间的血液滤过是控制液体平衡的一种有价值的方法。它有助于终末期肾衰竭或术前肺水肿患者的术中及术后管理。通过测量EVLW证明，HF似乎有助于降低诸如液体过载等并发症的风险。
