Kellum John A
The CRISMA (Clinical Research Investigation and Systems Modeling of Acute Illness) Laboratory, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Crit Care. 2005 Oct 5;9(5):500-7. doi: 10.1186/cc3789. Epub 2005 Aug 5.
Recent advances in acid-base physiology and in the epidemiology of acid-base disorders have refined our understanding of the basic control mechanisms that determine blood pH in health and disease. These refinements have also brought parity between the newer, quantitative and older, descriptive approaches to acid-base physiology. This review explores how the new and older approaches to acid-base physiology can be reconciled and combined to result in a powerful bedside tool. A case based tutorial is also provided.
酸碱生理学和酸碱平衡紊乱流行病学的最新进展，使我们对健康和疾病状态下决定血液pH值的基本控制机制有了更深入的理解。这些进展还使酸碱生理学中较新的定量方法和较旧的描述性方法达到了平衡。本综述探讨了如何将酸碱生理学的新旧方法进行协调和结合，从而形成一种强大的床边工具。同时还提供了一个基于病例的教程。
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