Brady Kathleen T, Verduin Marcia L
Institute of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
Subst Use Misuse. 2005;40(13-14):2021-41, 2043-8. doi: 10.1080/10826080500294924.
Mood and anxiety disorders commonly co-occur with substance use disorders. Exploration of the neurobiology of substance use disorders and mood and anxiety disorders have found that the neural circuitry in mood, anxiety, and substance use disorders is clearly overlapping. These discoveries have encouraged the exploration of a number of pharmacotherapeutic agents in the treatment of co-occurring mood, anxiety, and substance use disorders. In this article, recent data on the pharmacotherapeutic treatment of mood and anxiety disorders in individuals with substance use disorders are reviewed. Some of the barriers to the use of pharmacotherapy in individuals with substance use disorders are discussed.
情绪和焦虑障碍通常与物质使用障碍同时出现。对物质使用障碍以及情绪和焦虑障碍的神经生物学研究发现，情绪、焦虑和物质使用障碍中的神经回路明显重叠。这些发现促使人们探索多种药物治疗剂来治疗同时出现的情绪、焦虑和物质使用障碍。在本文中，我们综述了有关物质使用障碍患者情绪和焦虑障碍药物治疗的最新数据。还讨论了在物质使用障碍患者中使用药物治疗的一些障碍。
