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阿伏苯宗的体外神经保护特性。

Neuroprotective properties of afobazol in vitro.

作者信息

Zenina T A, Gavrish I V, Melkumyan D S, Seredenina T S, Seredenin S B

机构信息

Department of Pharmacological Genetics, V. V. Zakusov State Research Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow.

出版信息

Bull Exp Biol Med. 2005 Aug;140(2):194-6. doi: 10.1007/s10517-005-0443-7.

Abstract

The effects of a novel selective anxiolytic afobazol on survival of HT-22 neurons were studied in the model of oxidative stress and glutamate toxicity. In both models, the neuroprotective effect of afobazol was established.

摘要

在氧化应激和谷氨酸毒性模型中研究了新型选择性抗焦虑药阿福唑对HT-22神经元存活的影响。在这两种模型中,均证实了阿福唑的神经保护作用。

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