Janahi Ibrahim A, Bener Abdulbari, Bush Andrew
Department of Pediatrics, Hamad Medical Corporation, Doha, State of Qatar.
Pediatr Pulmonol. 2006 Jan;41(1):80-6. doi: 10.1002/ppul.20331.
The aim of the present study is to determine the prevalence of asthma and allergic diseases among schoolchildren aged 6-14 years in the State of Qatar, based on a questionnaire designed by the International Study of Asthma and Allergy in Childhood (ISAAC). A cross-sectional study of 3,283 school children living in both urban and rural areas (average age, 9.03 +/- 1.99 years; 52.3% boys and 47.7% girls) was conducted between February 2003-February 2004. The population sample had a high prevalence of diagnosed asthma (19.8%), allergic rhinitis (30.5%), eczema (22.5%), and chest infection (11.9%). The frequency of asthma, allergic rhinitis, and eczema among parents reflected the same pattern as seen in their children. Overall, males had more asthma, allergic rhinitis, and chest infections than females. In general, the prevalence rate of asthma and allergic rhinitis decreased with age. The prevalence rate of asthma was significantly higher in mothers (11.8%) than in fathers (9.0%), but the frequency of allergic rhinitis symptoms was comparable (mothers, 18.5%; fathers, 17.5%). The prevalence rate of asthma (19.8%) in Qatari schoolchildren is very close to that in the neighboring Gulf country, Oman (20.7%), and higher than in some developing countries. Genetic factors related to the high rates of consanguinity may play an important role in the high prevalence rates noted in the Qatari population, but changes in lifestyle and environmental factors cannot be discounted as possible causes of the high prevalence noted in this study.
本研究的目的是根据儿童哮喘和过敏国际研究(ISAAC)设计的问卷,确定卡塔尔国6至14岁学童中哮喘和过敏性疾病的患病率。2003年2月至2004年2月期间,对3283名居住在城市和农村地区的学童(平均年龄9.03±1.99岁;男孩占52.3%,女孩占47.7%)进行了横断面研究。该人群样本中确诊哮喘(19.8%)、过敏性鼻炎(30.5%)、湿疹(22.5%)和胸部感染(11.9%)的患病率较高。父母中哮喘、过敏性鼻炎和湿疹的发病频率与他们孩子的情况相同。总体而言,男性患哮喘、过敏性鼻炎和胸部感染的比例高于女性。一般来说,哮喘和过敏性鼻炎的患病率随年龄增长而降低。母亲中哮喘的患病率(11.8%)显著高于父亲(9.0%),但过敏性鼻炎症状的发生频率相当(母亲为18.5%,父亲为17.5%)。卡塔尔学童中哮喘的患病率(19.8%)与邻国海湾国家阿曼(20.7%)非常接近,且高于一些发展中国家。与高近亲结婚率相关的遗传因素可能在卡塔尔人群中高患病率中起重要作用,但生活方式和环境因素的变化也不能排除是本研究中高患病率的可能原因。