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弗罗茨瓦夫人群中青光眼的患病率。弗罗茨瓦夫流行病学研究。

Prevalence of glaucoma in the wroclaw population. The wroclaw epidemiological study.

作者信息

Nizankowska Maria H, Kaczmarek Radoslaw

机构信息

Department of Ophthalmology, Wroclaw Medical University, Wroclaw, Poland.

出版信息

Ophthalmic Epidemiol. 2005 Dec;12(6):363-71. doi: 10.1080/09286580500212904.

Abstract

PURPOSE

Primarily to determine the prevalence of various types of glaucoma and ocular hypertension in Wroclaw inhabitants aged 40-79 years. The second aim of the study was to determine the number of undiagnosed glaucoma cases in this population.

METHODS

A representative group of the Wroclaw population (4853 people aged from 40 to 79 years) was recruited by a proportional simple random sampling selection with stratification. All participants underwent the first, screening-stage examination, which included a medical history interview, intraocular pressure (IOP) measurement, anterior chamber depth assessment by the Van Herrick technique, and optic nerve head (ONH) assessment by means of indirect ophthalmoscopy (Volk's lens), confocal scanning laser ophthalmoscopy with a Heidelberg Retinal Tomograph (HRT) and scanning laser polarimetry by the GDx Nerve Fiber Analyzer (GDx). The second stage, in glaucoma-suspect patients only, included best corrected visual acuity, static perimetry, 24-hour monitoring of IOP, gonioscopy, and full eye examination with mydriasis. Glaucoma was diagnosed by the presence of any two of the following: characteristic morphological changes in the optic disc, glaucomatous visual field abnormalities, and intraocular pressure greater than 21 mmHg.

RESULTS

The overall prevalence of glaucoma was 1.6% (79 subjects). The prevalence increased with age from 0.4% in subjects belonging to the age group 40-49 years to 4.6% in people aged between 70 and 79 years. The prevalence of definite primary open-angle glaucoma was 1.0% (49 subjects). Normal-pressure glaucoma was diagnosed in 13 subjects (0.3%). Ocular hypertension was diagnosed in 92 subjects (1.9%).

CONCLUSION

The prevalence of the different types of glaucoma was similar to that found in other white populations. Among the subjects examined, 79 had various forms of glaucoma and 71% of them had not previously been diagnosed. Undiagnosed glaucoma is a serious public health problem in Poland.

摘要

目的

主要确定弗罗茨瓦夫40 - 79岁居民中各类青光眼和高眼压症的患病率。该研究的第二个目的是确定该人群中未被诊断出的青光眼病例数。

方法

通过分层比例简单随机抽样选取弗罗茨瓦夫人群中的一个代表性群体(4853名年龄在40至79岁之间的人)。所有参与者都接受了第一阶段的筛查检查,包括病史询问、眼压(IOP)测量、采用范·赫里克技术进行前房深度评估以及通过间接检眼镜( Volk 透镜)、使用海德堡视网膜断层扫描仪(HRT)的共焦扫描激光检眼镜和GDx神经纤维分析仪(GDx)进行的视神经乳头(ONH)评估。第二阶段仅针对疑似青光眼患者,包括最佳矫正视力、静态视野检查、眼压24小时监测、前房角镜检查以及散瞳后的全眼检查。青光眼的诊断依据为出现以下任意两项:视盘特征性形态改变、青光眼性视野异常以及眼压高于21 mmHg。

结果

青光眼的总体患病率为1.6%(79名受试者)。患病率随年龄增长而增加,从40 - 49岁年龄组受试者的0.4%增至70至79岁人群的4.6%。明确的原发性开角型青光眼患病率为1.0%(49名受试者)。13名受试者(0.

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