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急诊科纤溶治疗急性心肌梗死的疗效

Efficacy of fibrinolysis in the emergency department for acute myocardial infarction.

作者信息

Lane G, Cuddihy J, Wright P, Doherty D, McShane A

机构信息

Emergency Dept, Letterkenny General Hospital.

出版信息

Ir J Med Sci. 2005 Jul-Sep;174(3):9-12. doi: 10.1007/BF03169140.

Abstract

BACKGROUND

Patients with an acute myocardial infarction require a rapid response to their symptoms and the earlier fibrinolysis is given (where indicated), the better the outcome.

AIMS

The aim of this study is to compare 'door to needle times' for fibrinolysis in Acute Myocardial Infarction (AMI) in three phases of one year each, at Letterkenny General Hospital.

METHODS

In the PREINTERVENTION year all fibrinolysis was performed in the Coronary Care Unit (CCU). In the INTERVENTION year Emergency Department (ED) fast track fibrinolysis was introduced and in the POST INTERVENTION year most fibrinolysis was performed on fast track in the ED.

RESULTS

The time saved by the introduction of ED fibrinolysis was significant, 41 minutes on average per patient. Elderly, female patients were more likely to bypass ED fast track fibrinolysis and to be brought to CCU for fibrinolysis, with attendant delays. This has educational implications in relation to the variation in clinical presentation of AMI with age and sex.

CONCLUSION

The ED fast track fibrinolysis system is recommended as an effective, safe, achievable and worthwhile intervention towards improving 'door to needle times' for fibrinolysis in AMI.

摘要

背景

急性心肌梗死患者需要对其症状做出快速反应,且(在有指征时)越早进行纤维蛋白溶解治疗,预后越好。

目的

本研究的目的是比较莱特肯尼综合医院在一年的三个阶段中,急性心肌梗死(AMI)患者纤维蛋白溶解治疗的“门到针时间”。

方法

在干预前的一年里,所有纤维蛋白溶解治疗均在冠心病监护病房(CCU)进行。在干预年引入了急诊科(ED)快速通道纤维蛋白溶解治疗,在干预后一年,大多数纤维蛋白溶解治疗在急诊科的快速通道上进行。

结果

引入急诊科纤维蛋白溶解治疗节省的时间显著,平均每位患者节省41分钟。老年女性患者更有可能绕过急诊科快速通道纤维蛋白溶解治疗,而被送往冠心病监护病房进行纤维蛋白溶解治疗,从而导致延误。这对于急性心肌梗死临床表现随年龄和性别的变化具有教育意义。

结论

推荐急诊科快速通道纤维蛋白溶解治疗系统,作为一种有效、安全、可实现且值得的干预措施,以改善急性心肌梗死患者纤维蛋白溶解治疗的“门到针时间”。

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