一种来自大戟科大戟的新愈创木烷二萜。
A new guaiane diterpenoid from Euphorbia wallichii.
作者信息
Zhang Xiaofeng, Wang Huan, Sheng Jianwei, Luo Xiaodong
机构信息
North West Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810001, P.R. China.
出版信息
Nat Prod Res. 2006 Jan;20(1):89-92. doi: 10.1080/14786410500045382.
PMID:16286316
Abstract
A new guaiane-type diterpenoid, (1alpha,5beta,7alpha)-3,10(18),11-dictytriene-19-acid, was obtained from the roots of Euphorbia wallichii. This is the first isolation of guaiane diterpene from this genus of Euphorbia. The structure was elucidated by spectral methods. And the compound was tested for the cytotoxicities on the cancer cell line P-388 and A-549 in vitro.
摘要
从大戟科大戟属植物瓦氏大戟的根中获得了一种新的愈创木烷型二萜，即(1α,5β,7α)-3,10(18),11-二歧三烯-19-酸。这是首次从该大戟属植物中分离出愈创木烷二萜。通过光谱方法阐明了其结构。并对该化合物进行了体外对癌细胞系P-388和A-549的细胞毒性测试。
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