Kuroi Katsumasa, Shimozuma Kojiro, Taguchi Tetsuya, Imai Hirohisa, Yamashiro Hiroyasu, Ohsumi Shozo, Saito Shinya
Department of Surgery, Showa University Toyosu Hospital, Koutou-ku, Tokyo 135-8577, Japan.
Breast Cancer. 2005;12(4):288-93. doi: 10.2325/jbcs.12.288.
Seroma is the most common complication of mastectomy. The aim of this systematic review is to clarify the pathophysiology of seroma.
A computer-assisted MEDLINE search was conducted, and additional references were found in the bibliographies of these articles. The reference terms ''breast cancer'', ''mastectomy'', ''seroma'', ''lymphocele'' and ''lymphocyst'' were used as both keyword and subject terms. The search was limited to studies published in English.
The definition of seroma was highly variable across studies, but was most commonly a seroma large enough to be noticed by the patient or medical staff and affecting the patient's satisfaction in the immediate or acute postoperative period. So far, only limited data are available on the severity of seroma. With respect to the pathophysiology of seroma, the data indicated that several anatomical factors, especially dead space, likely contribute to seroma formation. However, it was obscure whether seroma was due to lymph-like fluid or exudate.
There is considerable variability in the way seroma is defined across studies, and its pathophysiology remains uncertain.
血清肿是乳房切除术最常见的并发症。本系统评价的目的是阐明血清肿的病理生理学。
进行了计算机辅助的MEDLINE检索，并在这些文章的参考文献中找到了其他参考文献。参考词“乳腺癌”“乳房切除术”“血清肿”“淋巴囊肿”和“淋巴管囊肿”用作关键词和主题词。检索限于以英文发表的研究。
各研究中血清肿的定义差异很大，但最常见的是血清肿大到足以被患者或医务人员注意到，并在术后即刻或急性期影响患者的满意度。到目前为止，关于血清肿严重程度的数据有限。关于血清肿的病理生理学，数据表明几个解剖学因素，尤其是死腔，可能促成血清肿的形成。然而，血清肿是由于淋巴样液体还是渗出液尚不清楚。
各研究中血清肿的定义方式存在很大差异，其病理生理学仍不确定。
