Tomimaru Yoshito, Komoike Yoshifumi, Egawa Chiyomi, Motomura Kazuyoshi, Inaji Hideo, Kataoka Tatsuki R, Koyama Hiroki
Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
Breast Cancer. 2005;12(4):322-6. doi: 10.2325/jbcs.12.322.
We report a case of phyllodes tumor (PT) with multiple lesions partly mimicking fibroadenoma (FA). A 43-year-old woman was referred to our institute because of a left breast mass which was diagnosed as FA clinically. During the follow-up, the mass gradually enlarged and excisional biopsy was performed to rule out malignant lesion. On histological examination, the tumor consisted of three different components; a lesion diagnosed as FA, another lesion as benign PT, and the other lesion as borderline PT. Finally, the tumor was diagnosed as borderline PT. Stromal cellularity may vary from area to area in any given PT. If there are some disagreements among the findings of imagings and cytology for the diagnosis of FA, as was seen in our case, the possibility of coexistence of PT should be considered.
我们报告一例叶状肿瘤(PT),其具有多个部分类似于纤维腺瘤(FA)的病变。一名43岁女性因左乳肿块被转诊至我院,该肿块临床诊断为FA。随访期间,肿块逐渐增大,遂行切除活检以排除恶性病变。组织学检查显示,肿瘤由三种不同成分组成;一个病变诊断为FA,另一个病变为良性PT,还有一个病变为交界性PT。最终,该肿瘤被诊断为交界性PT。在任何给定的PT中,间质细胞密度可能因区域而异。如果在FA诊断的影像学和细胞学检查结果之间存在一些分歧,如我们的病例所示,则应考虑PT共存的可能性。