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1
Five-Year Disease-Free Follow-Up of a Borderline Breast Phyllodes Tumor in a 15-year-old Patient.一名15岁患者的乳腺交界性叶状肿瘤的五年无病随访
J Breast Health. 2015 Jul 1;11(3):138-140. doi: 10.5152/tjbh.2015.2146. eCollection 2015 Jul.
2
Case report: Transformation of juvenile fibroadenoma to borderline phyllodes tumor in young lady.病例报告：年轻女性的幼年型纤维腺瘤转变为交界性叶状肿瘤。
Int J Surg Case Rep. 2021 Jul;84:106143. doi: 10.1016/j.ijscr.2021.106143. Epub 2021 Jun 30.
3
Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior.乳腺叶状肿瘤：一种临床行为难以预测的肿瘤。
Cureus. 2023 Apr 13;15(4):e37537. doi: 10.7759/cureus.37537. eCollection 2023 Apr.
4
Predictive factors of local recurrence and survival following primary surgical treatment of phyllodes tumors of the breast.乳腺叶状肿瘤初次手术治疗后局部复发及生存的预测因素。
J Egypt Natl Canc Inst. 2006 Jun;18(2):125-33.
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Comparison of clinical characteristics between benign borderline and malignant phyllodes tumors of the breast.乳腺良性、交界性及恶性叶状肿瘤的临床特征比较。
Asian Pac J Cancer Prev. 2014;15(24):10791-5. doi: 10.7314/apjcp.2014.15.24.10791.
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Phyllodes tumors of the breast: The British Columbia Cancer Agency experience.乳腺叶状肿瘤：不列颠哥伦比亚癌症机构的经验
Cancer Radiother. 2018 Apr;22(2):112-119. doi: 10.1016/j.canrad.2017.08.112. Epub 2018 Mar 7.
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Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin.乳腺叶状肿瘤：间质过度生长和组织学分类是手术切缘阳性患者局部复发的有用预后预测因素。
Jpn J Clin Oncol. 2007 Oct;37(10):730-6. doi: 10.1093/jjco/hym099. Epub 2007 Oct 11.
8
Management of phyllodes breast tumors.乳腺叶状肿瘤的处理。
Breast J. 2011 Mar-Apr;17(2):129-37. doi: 10.1111/j.1524-4741.2010.01045.x. Epub 2011 Jan 19.
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Phyllodes tumors of the breast: Analysis of 35 cases from a single institution.乳腺叶状肿瘤：来自单一机构的35例病例分析。
J Egypt Natl Canc Inst. 2016 Dec;28(4):243-248. doi: 10.1016/j.jnci.2016.06.004. Epub 2016 Jul 9.
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Recurrent giant fibroadenomas with transformation to cystosarcoma phyllodes in a 17-year-old girl: a rare case report from Syria.一名17岁女孩复发性巨大纤维腺瘤伴转化为叶状囊肉瘤：叙利亚的一例罕见病例报告
J Med Case Rep. 2019 Dec 21;13(1):378. doi: 10.1186/s13256-019-2313-3.

本文引用的文献

1
Long-term follow-up result of benign phyllodes tumor of the breast diagnosed and excised by ultrasound-guided vacuum-assisted breast biopsy.超声引导下真空辅助乳腺活检诊断并切除的乳腺良性叶状肿瘤的长期随访结果。
J Breast Cancer. 2012 Jun;15(2):224-9. doi: 10.4048/jbc.2012.15.2.224. Epub 2012 Jun 28.
2
Coexistence of benign phyllodes tumor and invasive ductal carcinoma in distinct breasts: case report.双乳内良性叶状肿瘤与浸润性导管癌共存：病例报告。
Eur J Med Res. 2012 Apr 25;17(1):8. doi: 10.1186/2047-783X-17-8.
3
[Phyllodes tumor in an 11 years-old girl: Report of a case].[一名11岁女孩的叶状肿瘤：病例报告]
Arch Argent Pediatr. 2010 Apr;108(2):e41-3. doi: 10.1590/S0325-00752010000200016.
4
Recent advances in systemic therapy: Advances in systemic therapy for HER2-positive metastatic breast cancer.近期全身治疗的进展：HER2 阳性转移性乳腺癌的全身治疗进展。
Breast Cancer Res. 2009;11(4):207. doi: 10.1186/bcr2324. Epub 2009 Jul 15.
5
Phyllodes tumor of the breast: an update.乳腺叶状肿瘤：最新进展。
Breast Cancer. 2010;17(1):29-34. doi: 10.1007/s12282-009-0114-z. Epub 2009 May 12.
6
Intratumoral hemorrhage of mammary phyllodes tumor after menstrual induction: a puzzling presentation.月经诱导后乳腺叶状肿瘤的瘤内出血：一种令人困惑的表现。
Tumori. 2007 Nov-Dec;93(6):631-3. doi: 10.1177/030089160709300622.
7
Phyllodes tumor with osteosarcomatous differentiation: a comparative immunohistochemical study between epithelial and mesenchymal cells.伴有骨肉瘤分化的叶状肿瘤：上皮细胞与间充质细胞的免疫组织化学对比研究
Tumori. 2006 Jul-Aug;92(4):340-6. doi: 10.1177/030089160609200414.
8
Phyllodes tumors of the breast: a case series of 106 patients.乳腺叶状肿瘤：106例病例系列
Am J Surg. 2006 Aug;192(2):141-7. doi: 10.1016/j.amjsurg.2006.04.007.
9
A case of phyllodes tumor of the breast with a lesion mimicking fibroadenoma.一例乳腺叶状肿瘤伴类似纤维腺瘤的病变。
Breast Cancer. 2005;12(4):322-6. doi: 10.2325/jbcs.12.322.
10
The diagnosis and management of pre-invasive breast disease: pathological diagnosis--problems with existing classifications.乳腺浸润前疾病的诊断与管理：病理诊断——现有分类存在的问题
Breast Cancer Res. 2003;5(5):269. doi: 10.1186/bcr629. Epub 2003 Jul 29.

一名15岁患者的乳腺交界性叶状肿瘤的五年无病随访

Five-Year Disease-Free Follow-Up of a Borderline Breast Phyllodes Tumor in a 15-year-old Patient.

作者信息

Güler Sertaç Ata, Uğurlu M Ümit, Güllüoğlu Bahadır M

机构信息

Department of General Surgery, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.

Department of General Surgery, Marmara University Faculty of Medicine, İstanbul, Turkey.

出版信息

J Breast Health. 2015 Jul 1;11(3):138-140. doi: 10.5152/tjbh.2015.2146. eCollection 2015 Jul.

DOI:10.5152/tjbh.2015.2146
PMID:28331709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5351453/
Abstract

Phyllodes tumors are large breast tumors representing only 1% of breast neoplasms and are rarely seen in young women. Histologically, phyllodes tumors are classified as benign, borderline, or malignant based on the characteristics of the stroma. Although wide local excision is recommended for the treatment modality, the reoccurrence rate after surgical excision varies between 36% and 65%, with recurrence more likely in those with the tumor at the margins of excision. Our aim was to report -a case in a 15-year-old girl with a 115-mm borderline phyllodes tumor in her left breast mimicking a juvenile fibroadenoma. We presented a 5-year disease-free follow-up after wide local excision with negative margins.

摘要

叶状肿瘤是一种较大的乳腺肿瘤，仅占乳腺肿瘤的1%，在年轻女性中很少见。从组织学上看，叶状肿瘤根据间质特征分为良性、交界性或恶性。尽管推荐广泛局部切除作为治疗方式，但手术切除后的复发率在36%至65%之间，肿瘤位于切除边缘的患者复发可能性更大。我们的目的是报告一例15岁女孩，其左乳有一个115毫米的交界性叶状肿瘤，酷似青少年纤维腺瘤。我们展示了广泛局部切除且切缘阴性后的5年无病随访情况。